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QCMD 400

The multichannel Quartz Crystal Microbalance with Dissipation, QCMD 400, offers time-saving operations and superior sensitivity in both frequency and dissipation. It enables the measurement of molecule-surface interactions across a wide range of applications.

Quantity

Key Highlights

  • 4 independent QuickLock cells for simultaneous measurements on four sensors

  • Individual control of each measurement cell, including temperature, sample solution, and flow rate

  • High-precision measurement of frequency and dissipation

  • Provides information on bound mass and layer viscoelasticity

  • Supports up to 7 overtones for comprehensive surface characterization

  • 4–160 MHz frequency range

  • 15–45°C temperature control

  • QuickLock cells for fast and easy sensor placement

  • Transparent cell lids allow direct observation of the sensor surface during measurement

  • Optional HFF-QCM flow cell for high-sensitivity, low-volume measurements down to 5.5 µL

  • Optional electrochemical cell for simultaneous QCM-D and electrochemical measurements

  • Supports additional static, in-batch, and dipping measurement modules

  • Precise syringe pumps provide individual flow control for each cell

Description

The QCMD 400 is a multichannel Quartz Crystal Microbalance with Dissipation (QCM-D) instrument designed for high-throughput, real-time characterization of molecule–surface interactions and thin-film properties. With four independent measurement cells, the system enables researchers to analyze four sensors simultaneously, significantly reducing measurement time. Each cell can be individually controlled for temperature, sample solution, and flow rate, allowing different experimental conditions to be evaluated in parallel. By simultaneously measuring changes in frequency and dissipation, the QCMD 400 provides quantitative information about bound mass and the viscoelastic properties of surface-bound layers. The system can also be equipped with high-frequency QCM sensors for enhanced sensitivity and low-volume measurements, as well as an electrochemical cell for combined QCM-D and electrochemical studies.

Specifications

Parameter

Specification

Measurement Principle

Quartz Crystal Microbalance with Dissipation (QCM-D)

Measurement Channels

4

QuickLock Cells

4

Simultaneous Sensors

4

Measurement Parameters

Frequency and dissipation

Number of Overtones

Up to 7 (fundamental + 6 overtones)

Frequency Range

4–160 MHz

Fixed-Frequency Measurement

Yes

Frequency Tracking / Scanning Mode

Yes

Temperature Control

15–45°C

Individual Cell Control

Temperature, sample solution, and flow rate

Syringe Pumps

Yes

Advanced Flow Control Unit

Optional

HFF-QCM Flow Cell

Optional

HFF-QCM Flow Cell Volume

5.5 µL

Electrochemical Cell

Optional

Other Measurement Modules

Static, in-batch, and dipping

Sensor Types

Classical QCMD, HFF-QCM, and LOVE-SAW

Transparent Cell Lid

Yes

Application

Biosensors Characterize biomolecular adsorption, binding, and surface interactions while monitoring changes in mass and viscoelastic properties in real time. Biomaterials Evaluate biomaterial–biomolecule interactions, surface modification, adsorption, and changes in the mechanical properties of surface layers. Biophysics Investigate molecular adsorption, thin-film formation, hydration, and viscoelastic behavior of biological layers. Layers & Coatings Characterize film formation, adsorption, layer thickness, hydration, and viscoelastic properties at solid–liquid interfaces. BioNavis identifies Layers & Coatings as a key QCMD application area. Electrochemistry Combine QCM-D with electrochemical measurements to monitor mass and viscoelastic changes during electrochemical processes using the optional electrochemical cell. Lipid & Membrane Research Study adsorption and formation of supported lipid layers and monitor associated frequency and dissipation changes. BioNavis uses supported lipid bilayer formation as an example application for its QCMD technology. Polymer & Soft Material Research Characterize adsorption, multilayer formation, hydration, and viscoelastic properties of polymers and other soft materials.

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