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BioNavis MP-SPR Navi™ 200 OTSO

Modular entry-level Multi-Parametric Surface Plasmon Resonance (MP-SPR) system for real-time interaction measurements and layer characterization.

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Key Highlights

  • Entry-level modular MP-SPR system for real-time interaction measurements and layer characterization

  • Open instrument design for integration with auxiliary instruments and customized experimental setups

  • Real-time, label-free analysis of molecular interactions

  • Measures binding affinity, binding kinetics, and bound mass without labeling

  • Up to 4 wavelengths per measurement channel for precise layer thickness and refractive index characterization

  • Wide angular range of 40°–78° for analyzing samples from small organic molecules and proteins to nanoparticles and cells

  • 2 independent fluidic channels for simultaneous measurements on a single sensor

  • 15–45°C temperature control

  • Easy sensor handling with elastomer-coated prisms

  • Modular add-on options for electrochemistry, high chemical resistance, live-cell, fluorescence, and gas-flow measurements

  • Supports PureKinetics™ for determining true binding kinetics without a reference channel

Description

The MP-SPR Navi™ 200 OTSO is a modular, entry-level Multi-Parametric Surface Plasmon Resonance (MP-SPR) system designed for real-time, label-free analysis of molecular interactions and surface properties. Its open design provides flexibility for integrating auxiliary instruments and developing customized experimental setups, making it particularly suitable for research, method development, and educational applications. The system features two fluidic channels and supports up to four wavelengths per channel, enabling the characterization of binding interactions, layer thickness, and refractive index. Its wide angular measurement range allows analysis of samples ranging from small organic molecules and proteins to metallic nanoparticles and cells. The modular platform can also be expanded with specialized flow cells for electrochemistry, high chemical-resistance measurements, live-cell studies, fluorescence, and gas-flow applications, providing flexibility for different research requirements.

Specifications

Parameter

Specification

Measurement Principle

Multi-Parametric Surface Plasmon Resonance (MP-SPR)

Measurement Mode

Real-time, label-free

Fluidic Channels

2

Angular Measurement Range

40°–78°

Wavelengths per Channel

Up to 4

Temperature Control

15–45°C

Pump

Peristaltic pump

Organic Solvent Compatibility

Optional

PureKinetics™

Yes

Layer Characterization

Thickness and refractive index

Interaction Analysis

Binding affinity, kinetics, and bound mass

Sensor Handling

Elastomer-coated prism

Optional Flow Cells

Electrochemistry, high chemical resistance, live cell, fluorescence, gas flow

Sensor Surfaces

Au, SiO₂, CMD, regenerable avidin, and other custom coatings

Application

Molecular Interaction Studies Real-time, label-free measurement of binding affinity, kinetics, and bound mass. Layers & Coatings Characterization of thin films and surface layers, including layer thickness and refractive index measurements. Multi-wavelength measurements can provide more detailed information about layer properties. Biosensors Investigation of biomolecular recognition and interactions on functionalized sensor surfaces. Nanoparticles Study of nanoparticle–surface and nanoparticle–biomolecule interactions. Biomaterials Characterization of interactions between biological molecules, cells, and material surfaces. Living Cell Research Real-time investigation of cell adhesion and cell–surface interactions under controlled temperature and flow conditions. Electrochemistry Combination of MP-SPR with electrochemical measurements using an optional electrochemistry flow cell. Research & Education Suitable for teaching and method-development environments where an open and flexible experimental platform is beneficial. BioNavis specifically identifies the open design as suitable for teaching purposes and integration with auxiliary instruments.

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