CRONUS | 2P

• Watt-level output at high repetition rates for fast imaging
• One or two tunable outputs and one fixed output for simultaneous multibeam excitation
• Automated GDD control for the shortest pulses at the sample
• Feedback-based output power and wavelength stabilization
• Beam steering & power locking

CRONUS-2P femtosecond lasers provide multiple watt-level synchronized outputs with high repetition rate, short pulse duration, and GDD control, making them the ultimate sources for nonlinear microscopy.

The microscopy-dedicated CRONUS-2P laser sources are available in the following configurations to meet diverse scientific requirements:

CRONUS-2P: Features one tunable output covering 700–1100 nm and one fixed output at 1025 nm, accessible in parallel, in a footprint as compact as 633 × 230 mm.
CRONUS-2P-XR: Offers one tunable output with an extended tuning range of 680–1300 nm and one fixed output at 1025 nm.
CRONUS-2P-DUAL: Provides two independently tunable outputs that can operate separately or simultaneously, covering 680 – 960 nm and 940 – 1300 nm, respectively, together with a third fixed output at 1025 nm.
Due to this versatility, CRONUS-2P femtosecond lasers enable simultaneous excitation of multiple fluorescent probes, calcium indicators, or opsins at their absorption maxima. Second- and third-harmonic generation (SHG and THG) signals can also be spectrally shifted to simplify detection or achieve resonant enhancement.

The tunable and synchronized outputs also enable advanced coherent anti-Stokes Raman scattering (CARS) and stimulated Raman scattering (SRS) applications. These include dual-band imaging, access to a broader range of vibrational resonances, constant-difference dual-beam tuning, resonant enhancement, and other advanced nonlinear imaging techniques.

Tunable Wavelength: 700–1100 nm / 680–1300 nm, model-dependent
Fixed Output: 1025 ± 10 nm
Output Power: Up to >2.5 W, model-dependent
Pulse Duration: <100–120 fs, model-dependent
Repetition Rate: 80 ± 0.5 MHz
Beam Quality (M²): <1.2
Polarization: Linear, horizontal
Power Stability: <1% over 8 h
GDD Control: Automated, wavelength-dependent

• Two-photon microscopy
• Multiphoton imaging
• Optogenetics
• CARS microscopy
• SRS microscopy
• SHG and THG microscopy
• Fluorescence imaging
• Nonlinear optical imaging