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CRONUS | 3P

Femtosecond Lasers for Advanced Nonlinear Microscopy

Quantity

Key Highlights

  • High pulse energy for deep imaging
  • 1250 – 1800 nm tuning range for 3P imaging
  • Down to 50 fs pulse duration for high peak power
  • Automated wavelength and GDD control for optimal signal
  • Maintenance-free single-box solution

Description

CRONUS-3P is a turnkey laser source developed for advanced nonlinear microscopy. It provides µJ-level pulses with durations down to 50 fs at repetition rates of up to 2 MHz. The pulses are tunable in the short-wavelength infrared (SWIR) range from 1250 to 1800 nm, covering the biological transparency windows at 1300 and 1700 nm essential for three-photon (3P) microscopy. Additionally, CRONUS-3P features integrated group delay dispersion (GDD) control, beam steering, and an optional simultaneous 1030 nm output.

Conventional multiphoton imaging in the SWIR range often requires complex multi-device laser systems, large optical tables, and skilled staff, creating barriers for neuroscience and other biomedical applications. CRONUS-3P addresses the challenges as a next‑generation, industrial-grade, single-supplier solution. Compact, reliable, and versatile, it offers tunable femtosecond excitation with GDD compensation to ensure optimal pulse duration at the sample. Its industrial-grade design guarantees high pulse-to-pulse energy and long-term power stability.

Specifications

Tuning Range: 1250–1800 nm
Repetition Rate: Single-shot to 1 or 2 MHz
Pulse Duration: <50 fs @ 1300 nm; <65 fs @ 1700 nm
Output Power: Up to >2 W at 1300 nm, model-dependent
GDD Control: −4500 to +500 fs² at 1300 nm; −12,000 to +3500 fs² at 1700 nm
Beam Quality: M² < 1.2
Long-Term Power Stability: <1% over 24 h
Pulse-to-Pulse Energy Stability: <1%

Application

  • Three-photon microscopy
  • Deep-tissue imaging
  • Functional neuroimaging
  • Neuroscience research
  • Multiphoton fluorescence imaging
  • SHG and THG microscopy
  • Nonlinear optical imaging
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