LigandTracer Yellow

• Estimate the affinity and kinetics of interactions with living cells

• Use regular "100 mm" Petri dishes of any brand (Ø:87-89 mm and h: 15-18 mm without the lid)

• Measure at room temperature, in incubators, or in cold rooms

• Plan your run and store relevant information with our intuitive control software

• Estimate interaction parameters with our versatile evaluation tool TraceDrawer

• Quickly advance your knowledge with LigandTracer Learning

LigandTracer® monitors molecular interactions in real-time, right on your lab bench, with only a few preparatory steps and limited input. The most common target is a cellular receptor expressed on the surface of living cells, but almost any interaction can be monitored as long as:

• You can label your ligand of interest

• Targets can be attached to a Petri dish

• The interaction occurs within minutes to hours

LigandTracer Yellow is equipped with a scintillator-based detector for high energy ɣ-photons (~0.1 – 1.5 MeV) and is suitable for the detection of all radionuclides used in PET/SPECT imaging. The following radionuclides have successfully been used for LigandTracer Yellow assays: 11C, 18F, 51Cr, 57Co, 64Cu, 67Ga, 68Ga, 89Zr, 90Y, 99mTc, 111In, 131I, 155Tb, 177Lu, 188Re, 212Pb and 223Ra. Detector: High-energy γ scintillator-based detector

• Drug discovery and development

• Antibody characterization

• Receptor–ligand interaction studies

• Affinity and kinetic analysis

• Receptor quantification

• Specificity and competition studies

• Receptor clustering and dimerization

• Drug conjugate characterization

• Radiotracer development

• Nanoparticle characterization

• Cell-based interaction studies

• Physiological process studies

• Screening and lead evaluation