MP-SPR NAVI™ 220A Naali
The MP-SPR Navi™ 220A NAALI is the most versatile MP-SPR instrument for interactions and layer characterization. Fully automated with a 96/384 well plate, it provides high throughput and is equipped with up to 4 wavelengths of light to ensure precise layer characterization. A full range of add-on modules is available, including electrochemistry, fluorescence, and cell flow cells.
Quantity
Key Highlights
Fully automated 2-channel MP-SPR system for real-time, label-free analysis
High-throughput measurements using 96- and 384-well microplates
Up to 4 wavelengths per measurement channel for advanced layer characterization
Measures binding affinity, binding kinetics, bound mass, film thickness, and refractive index
Wide angular range of 40°–78° for analysis of small molecules, proteins, nanoparticles, and cells
Parallel and serial sample injections across two independent fluidic channels
Unattended operation with automated liquid handling, integrated degassing, and precision syringe pumps
Modular add-ons for electrochemistry, fluorescence, live-cell, gas, and high chemical-resistance measurements
Temperature control from 15–45°C
Compatible with a wide range of sensor surfaces and functionalized coatings
Description
The MP-SPR Navi™ 220A NAALI is a fully automated Multi-Parametric Surface Plasmon Resonance (MP-SPR) instrument designed for high-throughput, real-time, label-free analysis of molecular interactions and surface properties. The system features two independent fluidic channels and an automated 96/384-well plate system, enabling efficient analysis of large sample sets with minimal user intervention. With support for up to four wavelengths per channel, the instrument provides detailed characterization of binding interactions, layer thickness, refractive index, and optical properties. Its modular design allows researchers to expand the system with specialized flow cells and modules for electrochemistry, fluorescence, live-cell analysis, gas-phase measurements, and chemically resistant applications. This makes the 220A NAALI suitable for a broad range of research in life science, biosensors, biomaterials, surface chemistry, and materials science.
Specifications
Parameter | Specification |
Measurement Principle | Multi-Parametric Surface Plasmon Resonance (MP-SPR) |
Measurement Mode | Real-time, label-free angular scanning |
Fluidic Channels | 2 |
Angular Measurement Range | 40°–78° |
Angular Resolution | 0.001° |
Wavelengths per Channel | Up to 4 |
Standard Wavelength | 670 nm |
Optional Wavelengths | 670, 785, 850, and 980 nm configurations |
Autosampler | 96-/384-well plate and 6-vial liquid handling |
Unattended Operation | Yes |
Buffer Degasser | Yes |
Syringe Pumps | Precision syringe pumps |
Temperature Control | 15–45°C |
Flow Rate | 1–1,000 µL/min |
Standard Flow Cell | 2-channel PDMS flow cell |
Flow Cell Volume | 1 µL |
Optional Flow Cells | Electrochemistry, fluorescence, live-cell, gas, high chemical resistance |
Organic Solvent Compatibility | Available with appropriate flow-cell configuration |
Sensor Surfaces | Au, SiO₂, CMD, and other functionalized surfaces |
Software | MP-SPR Navi™ Controller / DataViewer; optional TraceDrawer™ |
Kinetic Analysis | Binding affinity and kinetic constants |
Layer Characterization | Film thickness and refractive index |
Application
Molecular Interactions Real-time analysis of molecular binding, affinity, kinetics, and bound mass without fluorescent or radioactive labels. Biosensor Development Characterization and optimization of sensing surfaces, receptor–analyte interactions, and label-free biosensing platforms. Biocompatibility Study of interactions between biomaterials, coatings, and biological molecules or cells. Biomaterials Characterization of surface properties, adsorption, molecular interactions, and functional coatings. Layers & Coatings Measurement of thin-film thickness, refractive index, adsorption, swelling, and other surface-layer properties. Nanoparticles Investigation of nanoparticle adsorption and interactions with surfaces or biomolecules. Living Cells Real-time investigation of cell adhesion and cell–surface interactions using dedicated cell flow-cell configurations. Electrochemistry Combination of MP-SPR with electrochemical measurements for studying surface and electrochemical processes. Drug Discovery & Pharmaceutical Research Analysis of biomolecular interactions and drug-related binding or surface processes, including high-throughput screening workflows.


