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MP-SPR NAVI™ 220A Naali

The MP-SPR Navi™ 220A NAALI is the most versatile MP-SPR instrument for interactions and layer characterization. Fully automated with a 96/384 well plate, it provides high throughput and is equipped with up to 4 wavelengths of light to ensure precise layer characterization. A full range of add-on modules is available, including electrochemistry, fluorescence, and cell flow cells.

Quantity

Key Highlights

  • Fully automated 2-channel MP-SPR system for real-time, label-free analysis

  • High-throughput measurements using 96- and 384-well microplates

  • Up to 4 wavelengths per measurement channel for advanced layer characterization

  • Measures binding affinity, binding kinetics, bound mass, film thickness, and refractive index

  • Wide angular range of 40°–78° for analysis of small molecules, proteins, nanoparticles, and cells

  • Parallel and serial sample injections across two independent fluidic channels

  • Unattended operation with automated liquid handling, integrated degassing, and precision syringe pumps

  • Modular add-ons for electrochemistry, fluorescence, live-cell, gas, and high chemical-resistance measurements

  • Temperature control from 15–45°C

  • Compatible with a wide range of sensor surfaces and functionalized coatings

Description

The MP-SPR Navi™ 220A NAALI is a fully automated Multi-Parametric Surface Plasmon Resonance (MP-SPR) instrument designed for high-throughput, real-time, label-free analysis of molecular interactions and surface properties. The system features two independent fluidic channels and an automated 96/384-well plate system, enabling efficient analysis of large sample sets with minimal user intervention. With support for up to four wavelengths per channel, the instrument provides detailed characterization of binding interactions, layer thickness, refractive index, and optical properties. Its modular design allows researchers to expand the system with specialized flow cells and modules for electrochemistry, fluorescence, live-cell analysis, gas-phase measurements, and chemically resistant applications. This makes the 220A NAALI suitable for a broad range of research in life science, biosensors, biomaterials, surface chemistry, and materials science.

Specifications

Parameter

Specification

Measurement Principle

Multi-Parametric Surface Plasmon Resonance (MP-SPR)

Measurement Mode

Real-time, label-free angular scanning

Fluidic Channels

2

Angular Measurement Range

40°–78°

Angular Resolution

0.001°

Wavelengths per Channel

Up to 4

Standard Wavelength

670 nm

Optional Wavelengths

670, 785, 850, and 980 nm configurations

Autosampler

96-/384-well plate and 6-vial liquid handling

Unattended Operation

Yes

Buffer Degasser

Yes

Syringe Pumps

Precision syringe pumps

Temperature Control

15–45°C

Flow Rate

1–1,000 µL/min

Standard Flow Cell

2-channel PDMS flow cell

Flow Cell Volume

1 µL

Optional Flow Cells

Electrochemistry, fluorescence, live-cell, gas, high chemical resistance

Organic Solvent Compatibility

Available with appropriate flow-cell configuration

Sensor Surfaces

Au, SiO₂, CMD, and other functionalized surfaces

Software

MP-SPR Navi™ Controller / DataViewer; optional TraceDrawer™

Kinetic Analysis

Binding affinity and kinetic constants

Layer Characterization

Film thickness and refractive index

Application

Molecular Interactions Real-time analysis of molecular binding, affinity, kinetics, and bound mass without fluorescent or radioactive labels. Biosensor Development Characterization and optimization of sensing surfaces, receptor–analyte interactions, and label-free biosensing platforms. Biocompatibility Study of interactions between biomaterials, coatings, and biological molecules or cells. Biomaterials Characterization of surface properties, adsorption, molecular interactions, and functional coatings. Layers & Coatings Measurement of thin-film thickness, refractive index, adsorption, swelling, and other surface-layer properties. Nanoparticles Investigation of nanoparticle adsorption and interactions with surfaces or biomolecules. Living Cells Real-time investigation of cell adhesion and cell–surface interactions using dedicated cell flow-cell configurations. Electrochemistry Combination of MP-SPR with electrochemical measurements for studying surface and electrochemical processes. Drug Discovery & Pharmaceutical Research Analysis of biomolecular interactions and drug-related binding or surface processes, including high-throughput screening workflows.

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