MP-SPR NAVI™ 400 Kontio

• 4 independent fluidic channels for simultaneous measurements on a single sensor

• Designed for cell adhesion and cell-based interaction studies

• Real-time, label-free measurement of binding affinity and kinetics

• Measures the complete SPR curve for comprehensive analysis of cell and molecular interactions

• Enables measurements under physiologically relevant conditions

• Precise control of temperature, flow rate, shear stress, and liquid composition

• Wide 40°–78° measurement range for complex samples such as cell culture media, serum, and saliva

• 2 wavelengths per measurement channel for enhanced surface characterization

• PureKinetics™ for determining true binding kinetics without requiring a reference channel

• Elastomer-coated prism enables ex situ cell layer growth and subsequent analysis using techniques such as AFM and microscopy

• Compatible with a wide range of sensor surfaces, including Au, SiO₂, CMD, and regenerable avidin surfaces

The MP-SPR Navi™ 400 KONTIO is a 4-channel Multi-Parametric Surface Plasmon Resonance (MP-SPR) instrument designed for real-time, label-free analysis of cell adhesion, cell-based interactions, and molecular binding. With four fluidic channels, the system enables simultaneous measurements on a single sensor while providing precise control of temperature, flow rate, shear stress, and liquid composition. These capabilities allow researchers to investigate cell–surface interactions under physiologically relevant conditions. The instrument captures the complete SPR curve, providing comprehensive information for analyzing molecular and cellular interactions. Its wide angular measurement range also enables measurements using complex samples such as cell culture media, serum, and saliva. The elastomer-coated prism facilitates convenient sensor handling and allows cell layers to be prepared ex situ for further characterization using complementary techniques such as AFM and microscopy.

Cell Adhesion & Cell–Surface Interactions Study cell attachment, adhesion, and interactions with surfaces in real time under controlled flow and physiological conditions. Cell-Based Interaction Studies Characterize interactions between living cells and biomaterials, coatings, or functionalized surfaces. Molecular Interactions Analyze label-free molecular binding, affinity, and kinetics in real time. Life Science & Cell Research Investigate cellular responses and interactions using relevant biological environments and complex samples. Biomaterials Evaluate interactions between cells, biological molecules, and biomaterial surfaces. Biosensors Characterize surface interactions and biological recognition processes in label-free biosensing systems. Complex Biological Samples Perform measurements using samples such as cell culture media, serum, and saliva, enabled by the instrument's wide angular measurement range.