QCMD 100

• Real-time, label-free measurement of molecule–surface interactions

• Simultaneous measurement of frequency and dissipation for comprehensive surface characterization

• Electrochemistry in-batch cell included for simultaneous QCM-D and electrochemical measurements

• QuickLock cell for fast and easy sensor placement

• Transparent cell lid allows direct observation of the sensor surface during measurement

• Supports up to 7 overtones (fundamental + 6 overtones)

• Frequency range of 4–160 MHz

• High-frequency HFF-QCM flow cell available for enhanced sensitivity and low-volume measurements

• HFF-QCM flow cell volume as low as 5.5 µL

• Modular design allows users to add functions according to research requirements

• Optional temperature and high-temperature/high-pressure modules

• Compatible with different sensor types, including conventional QCMD, HFF-QCM, and LOVE-SAW sensors

The QCMD 100 is a modular Quartz Crystal Microbalance with Dissipation (QCM-D) instrument designed for real-time, label-free characterization of molecular interactions and thin films at surfaces. By simultaneously monitoring changes in resonant frequency and energy dissipation, the system provides information about mass changes as well as the viscoelastic properties, hydration, thickness, and mechanical behavior of surface-bound layers. This makes QCMD particularly useful for studying biomolecular adsorption, thin-film formation, surface chemistry, and material interfaces. The QCMD 100 includes an electrochemistry in-batch cell, enabling simultaneous electrochemical and QCM-D measurements. Its modular architecture also allows additional capabilities, such as high-frequency QCM measurements, temperature control, and specialized flow cells, to be added as research requirements evolve. The QuickLock cell simplifies sensor placement, while the transparent lid allows researchers to observe the sensor during measurements. For applications requiring high sensitivity and low sample volumes, the optional HFF-QCM flow cell provides a measurement volume of approximately 5.5 µL.

Electrochemistry Combine QCM-D with electrochemical measurements to monitor mass and viscoelastic changes during electrochemical processes. BioNavis demonstrates applications including Li-ion intercalation/deintercalation in battery electrodes, electrodeposition, electropolymerization, and surface functionalization. Biomolecular Interactions Study adsorption and interactions of proteins, biomolecules, and other compounds at solid–liquid interfaces. Biosensor Development Characterize immobilized biomolecules, surface coatings, hydration, rigidity, and stability of biosensor interfaces. Thin Films & Coatings Monitor film formation, adsorption, layer thickness, hydration, and viscoelastic properties in real time. Biophysics & Lipid Research Study lipid adsorption, liposome deformation, and supported lipid bilayer formation. BioNavis has demonstrated QCMD measurements of supported lipid bilayers on SiO₂-coated sensors. Polymers & Soft Materials Characterize polymer adsorption, multilayer assembly, hydration, and mechanical properties of soft films. Materials Science Investigate surface modification, adsorption processes, film formation, and material–liquid interactions. Battery & Energy Materials Monitor mass and structural changes associated with electrochemical processes in battery electrode materials.